HRaDeX is a part of tool family for analysing HDX-MS data, HaDeXversum. It is developed in Mass Spectrometry Lab in Institute of Biophysics and Biochemistry, Polish Acadamy of Sciences.
HRaDeX is a package for classification process of peptide-level uptake curves. While HRaDeX covers all computational processes, there are two GUIs for its functionalities. HRaDeXGUI is an app that allows one-state classification process. compaHRaDeX is an app for comparative analysis of classification results for two biological states, conducted separately using HRaDeXGUI.
The applications are available for use online: HRaDeX and compaHRaDeX.
The project is currently under development.
For more information on pepitde-level analysis, see documentation for HaDeX. For detailed explanation of the classification workflow works see this article. and of visualization the results, see this article. The documentation is available here.
Installation
HRaDeX can be downloaded directly from GitHub repository:
# install.packages("devtools")
devtools::install_github("hadexversum/HRaDeX")